PE anti-human Sialyl Lewis X (dimeric)
Description
The FH6 antibody recognizes Sialyl Lewis X (demeric) on glycolipids or glycoproteins. It also recognizes Sialyl Lewis X with long carbohydrate attachments (Sialyl Lewis X-i). These antigens are expressed on human granulocytes, monocytes, small subsets of lymphocytes, some fetal tissues such as the fetal stomach, fetal colon, and fetal intestine, and a variety of cancer tissues. It is believed that these antigens are involved in cell adhesion.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 microL per million cells or 5 microL per 100 microL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
References
1. Fukushi Y, et al. 1984. J. Biol. Chem. 259:10511.
2. Fukushi Y, et al. 1985. Cancer Res. 8:3711.
3. Kannagi R, et al. 1986. Cancer Research 5:2619.
4. Kobayashi M, et al. 2010. Anticancer Res. 30:593.