PE anti-mouse CD71

Antibodies Single
Sony
RI7217
Flow Cytometry
Rat IgG2a, κ
Mouse
1169035
$93.00

Description

CD71 is a 95 kD type II heterodimeric transmembrane glycoprotein that is also known as T9 and transferrin receptor. CD71 is expressed on proliferating cells, reticulocytes, and erythroid precursors. Its expression is very low on resting leukocytes. CD71 plays a role in the control of cellular proliferation by facilitating the uptake of iron via ferrotransferrin binding and the recycling of apotransferrin to the cell surface.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 microg per 106 cells in 100 microL volume. It is recommended that the reagent be titrated for optimal performance for each application.

References

1. Trowbridge I, et al. 1982. J. Cell. Physiol. 112:403.
2. Grisendi S, et al. 2005. Nature 437:147.
3. van Rooy I, et al. 2010. J. Control Release 150:30. PubMed
4. Willhelm BT, et al. 2011. Blood 117:27. PubMed
5. Okasi Y, et al. 2012. Exp Hematol. 40:143PubMed
6. Stojanov K, et al. 2012. Mol Pharm. 9:1620. PubMed