FITC anti-human Granzyme A

Antibodies Single
Sony
CB9
Flow Cytometry
Mouse IgG1, κ
Human
Purified human Granzyme A
100 tests
3136020
$237.00

Description

Granzyme A is a 28 kD disulfide-linked homodimeric protein and the most abundant of the proteases occurring in CTL granules. It is homologous to other serine esterases, including other granyzmes, mast cell proteases, and neutrophil cathepsins. Granzyme B is thought to be a rapidly-acting apoptotic enzyme, while Granzyme A is slow acting. The CB9 monoclonal antibody recognizes human Granzyme A and has been shown to be useful for flow cytometry, immunoprecipitation, and immunohistochemistry (paraffin-embedded sections).

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).

Recommended Usage

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. Test size products are transitioning from 20 microL to 5 microL per test. Please check your vial or your CoA to find the suggested use of this reagent per million cells in 100 microL staining volume or per 100 microL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

References

1. Trimble L, et al. 1998. Blood 91:585.
2. Beresford P, et al. 1997. P. Natl. Acad. Sci. USA 94:9285.
3. Raqib R, et al. 2002. Infect. Immun. 70:3199.
4. Chen H, et al. 2005. J. Immunol. 175:591.
5. Xu X, et al. 2012. PLoS One. 7:e41869. PubMed.