Purified anti-human CD282 (TLR2)

Antibodies Single
Sony
TL2.1
Other
Mouse IgG2a, κ
Human
Human TLR2-transfected CHO cells
100 µg
2148510
$267.00

Description

Toll-like receptors are type I transmembrane signaling receptors which are critical for the innate host defense to pathogens. Toll-like receptor 2 (TLR2), known as CD282, has been identified as a receptor that is central to the innate immune system's response to lipoproteins of Gram-negative bacteria and Gram-positive bacteria, as well as a receptor for peptidoglycan and lipoteichoic acid and other bacterial cell membrane products.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 microg per million cells in 100 microL volume. It is recommended that the reagent be titrated for optimal performance for each application.

References

1. Flo T, et al. 2000. J. Immunol. 164:2064.
2. Faure E, et al. 2001. J. Immunol. 166:2018.
3. Sugawara S, et al. 2001. Infect. Immun. 69:4951.
4. Droemann D, et al. 2003. Histochem. Cell Biol. 119:103.
5. Chavakis E, et al. 2007. Circ. Res. 100:204.PubMed
6. Fiala M, et al. 2007. Proc. Natl. Acad. Sci. USA 10.1073/P. Natl. Acad. Sci. USA.0701267104.
7. Goo SY, et al. 2007. J. Biol. Chem. doi:10.1074/jbc.M701876200.PubMed
8. Weiss DJ,et al. 2008.J. Leukoc. Biol. 83:48. PubMed
9. Harris, KM., et al. 2011. J. Leukoc Biol. 90:727. PubMed.
10. Elass-Rocahrd E, et al. 2012. J Biol Chem. 287:34432. PubMed.