PE anti-mouse CD195 (CCR5)

Antibodies Single
Sony
HM-CCR5
Flow Cytometry
Hamster IgG
Mouse
1135025

Description

CD195 is a 45 kD chemokine receptor also known as CCR5. CD195 is a seven transmembrane-spanning G protein-associated molecule expressed on macrophages, a T cell subset, and in the heart, liver, and spleen. CD195 regulates lymphocyte chemotaxis and transendothelial migration during inflammatory processes. CD195 interacts with several ligands including RANTES, MCP-1, MIP-1α, and MIP-1β.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 microg per million cells in 100 microL volume. It is recommended that the reagent be titrated for optimal performance for each application.

References

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6. Richardson ML, et al. 2014. PLoS Negl Trop Dis. 8:2825. PubMed
7. Nacer A, et al. 2014. PLoS Pathog. 10:1004528. PubMed
8. Fend L, et al. 2014. Cancer Immunol Res. 2:1163. PubMed