PerCP/Cy5.5 anti-human CD371 (CLEC12A)

Antibodies Single
Sony
50C1
Flow Cytometry
Mouse IgG2a, κ
Human
293T cells expressing CLEC12A-Flag
2368055
$174.00

Description

CD371 (CLEC12A), also known as DCAL-2, MICL or CLL-1, is a 30 kD type II transmembrane protein with extracellular C-type lectin domains, belonging to the C-type lectin family.  It is expressed on monocytes, granulocytes, NK cells, and basophils.  Its cytoplasmic ITIM motif modulates signaling cascades and is involved in phosphorylation of tyrosine residues in MAP kinases.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 microL per million cells or 5 microL per 100 microL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

* PerCP/Cy5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.

References

1. Lahoud MH, et al. 2009. J. Immunol. 182:7587. (FC)
2. Lahoud MH, et al. 2011. J. Immunol. 187:842. (FC)
3. Neumann K, et al. 2014. Immunity. 40:389. PubMed