PerCP/Cy5.5 anti-human HLA-E

Antibodies Single
Sony
3D12
Flow Cytometry
Mouse IgG1, κ
Human
2313050
$376.00

Description

HLA-E is a non-classical MHC class I (MHC-Ib) molecule. It is characterized by limited polymorphism and ubiquitous expression. HLA-E, as other MHC-I molecules, is heterodimerized with β2-microglobulin. HLA-E interacts with CD94/NKG2 receptor to regulate NK cell cytolysis activities.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 microL per million cells or 5 microL per 100 microL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

* PerCP/Cy5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.

References

1. Lee N, et al. 1998. Proc. Natl. Acad. Sci. USA. 95:5199.
2.
Wooden SL, et al. 2005. J. Immunol. 175:1383.
3.
Monaco EL, et al. 2008. J. Immunol. 181:5442.
4. Corrah TW, et al. 2011. J. Virol. 85:3367. PubMed