PE anti-human IL-13

Antibodies Single
Sony
JES10-5A2
Flow Cytometry
Rat IgG1, κ
Human
COS-expressed, recombinant human IL-13
25 tests
3109515
$105.00

Description

IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 lymphocytes. IL-13 shares 30% amino acid sequence homology with IL-4 and demonstrates similar biological activities. The biological activities of IL-13 include: suppression of macrophage cytotoxic activity, upregulation of IL-1RA expression, and suppression of proinflammatory cytokine secretion. The JES10-5A2 antibody reacts with human interleukin-13 (IL-13). The JES10-5A2 antibody can neutralize the bioactivity of natural or recombinant IL-13.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide, 0.2% (w/v) BSA (USA origin).

Recommended Usage

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. Test size products are transitioning from 20 microL to 5 microL per test. Please check your vial or your CoA to find the suggested use of this reagent per million cells in 100 microL staining volume or per 100 microL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

References

1. McKenzie, A., et al. 1994. Curr. Prot. Immunol.. John Wiley & Sons. New York. Section 6.18.
2. Abrams, J. 1995. Curr. Prot. Immunol.. John Wiley and Sons, New York. Unit 6.20.
3. Schaerli, P., et al. 2000. J. Exp. Med. 192:1553.
4. Andersson, J., et al. 1994. Immunology 83:16.
5. Skansen-Saphir, U., et al. 1994. Eur. J. Immunol. 24:916.
6. Andersson, U., et al. 1999. Detection and quantification of gene expression. New York:Springer-Verlag.
7. Gelfand, E. W., et al. 2006. J. Aller. and Clinic. Immunol. 117:577.
8. Knorr, C., et al. 1999. Am. J. Pathol. 155:2019.
9. Kongsbak M, et al. 2014. PLoS One. 9:96695. PubMed