PerCP/Cy5.5 anti-human IL-9

Antibodies Single
Sony
MH9A4
Flow Cytometry
Mouse IgG2b, κ
Human
Baculovirus-expressed, recombinant human IL-9
3138045
$134.00

Description

IL-9 is a potent, T cell-derived, T cell growth factor which can also enhance mast cell activity and IL-3- or IL-4- dependent proliferation of bone marrow-derived mast cells. IL-9 synergizes with erythropoietin to promote erythroid colony formation. IL-9 has also been reported to protect human T cells from apoptosis induced by IL-2 withdrawal. IL-9 is upregulated in human eosinophils by TNF-α and IL1-β. IL-9 has been reported to downregulate the oxidative burst in activated human alveolar macropahges and induce TGF-β production. The MH9A4 antibody reacts with human IL-9. The MH9A4 antibody can neutralize the bioactivity of natural or recombinant IL-9.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).

Recommended Usage

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 microL per million cells or 5 microL per 100 microL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

* PerCP/Cy5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.

References

1. Jenmalm M, et al. 2001. Clin. Exptl. Aller. 31:1528.
2. Faulkner H, et al. 2002. J. Infec. Diseas. 185:665.
3. Chen J, et al. 2008. Blood 111:5163. PubMed
4. Chang HC, et al. 2010. Nat. Immunol. 11:527. (ELISA) PubMed
5. Lozano E, et al. 2012. J Immunol. 188:3869. PubMed.