Biotin anti-mouse CD83

Antibodies Single
Sony
Michel-19
Flow Cytometry
Rat IgG1, κ
Mouse
Recombinant mouse CD83 protein
1207515
$105.00

Description

CD83 is a 45 kD type I transmembrane protein. It belongs to immunoglobulin superfamily and is expressed on mature dendritic cells and activated lymphocytes. CD83 is involved in the regulation of T cell development and immune response. Soluble form CD83 has been reported to inhibit dendritic cell maturation and dendritic cell-mediated T cell proliferation. Murine CD83 ligand has been found on B cells.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 microg per million cells in 100 microL volume. It is recommended that the reagent be titrated for optimal performance for each application.

References

1. Cramer SO, et al. 2000. Int. Immunol. 12:1347.
2. Fujimoto Y, et al. 2002. Cell 108:755.
3. Mott KR, et al. 2009. Virol J. 6:56. (FC) PubMed
4. Roland Cl, et al. 2009. Mol Cancer Res. 8:1761. (IHC) PubMed
5. Masuda Y, et al. 2010. Cancer Immunol Immunother. [Epub ahead of print] (FC) PubMed
6. Tze LE, et al. 2011. J Exp Med. PubMed
7. del Rio ML, et al. 2011. Transpl. Int. 24:501. (FC) PubMed