Alexa Fluor® 488 anti-IRF4

Antibodies Single
Sony
IRF4.3E4
Flow Cytometry
Rat IgG1, κ
Human,Mouse
GST fusion protein containing C-terminal of murine IRF4
3832030
$365.00

Description

The IRF family consists of at least nine members. IRF4 and IRF8 are highly homologous to each other and also redundant in function. IRF4 is critical for Th2 and Th17 development. Together with TRF8, it plays an essential role in macrophage and dendritic cell development and function. IRF4 is also reported to be essential for pre-B cell development, receptor editing, germinal center reactor and plasma cell differentiation.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Recommended Usage

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining using our nuclear factor staining protocol. For flow cytometric staining, the suggested use of this reagent is ≤0.125 microg per million cells in 100 microL volume. It is recommended that the reagent be titrated for optimal performance for each application.

* Alexa Fluor® 488 has a maximum emission of 519 nm when it is excited at 488 nm.

References

1. Zheng Y, et al. 2009. Nature 458:351
2. Yin SY, et al. 2011. Exp Cell Res. 317:2210. PubMed