About Sony Biotechnology

  • Allergic Inflammation: Cell Signaling and Epigenetic Mechanisms Underpinning Inflammatory Responses

    28 Jan 2020

    As the global prevalence of allergic inflammation continues to rise, efforts towards discovery of novel therapeutic modalities are very significant. Canadian immunologist Dr. MacNeil and his team pursue this using flow cytometry to identify the mechanism of allergy induced inflammation. Using the Sony SH800 cell sorter, Dr. MacNeil's lab sorts hematopoetic stem cells for immune profiling of the activated mast cell population. Individual cells from this population are sorted into a 96-well plate— for studying genetic and epigenetic basis of allergic response.


  • Webinar: Spectral Flow Cytometry for Deeper Insights

    21 Jan 2020

    Join us in this educational webinar to review the basic principles of spectral flow cytometry and understand how users of all expertise levels can easily design panels for high-parameter experiments to achieve a greater depth of information. This webinar will highlight how spectrally adjacent fluorochromes, fluorescent proteins, and fluorochromes excited by multiple lasers can be easily incorporated into a panel when using Sony spectral systems.


  • Webinar: Combinatorial Indexing: A High-Throughput Scalable Approach for Exploring Single-Cell Epigenomics

    02 Dec 2019

    Join our free educational webinar to learn from an eminent researcher how Single-Cell Combinatorial Indexing (SCI) can be used for assessment of the open chromatin landscape of single cells.


  • Webinar: An Accelerated Discovery Pipeline for Antiviral Antibody Therapeutics

    24 Oct 2019

    Learn how researchers have implemented accelerated discovery and validation of potent therapeutic mAbs using an integrated pipeline technology combining flow cytometry, bioinformatics, synthetic biology, and high-throughput analysis.


  • Webinar: Multi-omics Approach to Understanding PD-L1 Resistance in Cancer

    15 Oct 2019

    Join this free webinar to learn how researchers are integrating cell sorting, RNA sequencing, ex-vivo phenotype profiling, and patient-derived xenografts to study the mechanisms of PD-L1 resistance in cancer.


  • Webinar: Cell Sorting Best Practices from the Experts

    30 Sep 2019

    Join Flow Cytometry Lab Directors – Peter Lopez and Rui Gardner for this Best Practices Webinar on how to achieve optimal results from cell sorting.


  • Sorting a 12-Color Immunophenotyping Panel with the MA900 Cell Sorter

    16 Sep 2019

    See the results of sorting a 12-color immunophenotyping panel for T-cell, B-cell, NK-cell, and monocyte subsets using the MA900 cell sorter. Learn more about how 4 lasers, 12 fluorescence parameters, and 4-way sorting can dramatically simplify operation to make sorting less subjective and improve reliability.


  • Webinar: Sample Preparation and Cell Isolation for Multiplexed, Single-Cell Sequencing Analysis

    06 Sep 2019

    Join this free webinar to learn how to optimize sample preparation and obtain quality data from a multiplexed, single-cell sequencing assay. Increasingly, single-cell sequencing is used to profile the transcriptome of rare cell populations, resolve antigen binding specificities of T cells, and trace distinct cell lineages in development.


  • Barcoding Nuclei to Illuminate Single-Cell Epigenetics

    30 Aug 2019

    Single-cell sequencing has proven invaluable to understanding the biology of heterogeneous samples such as brain or tumor tissues. However, sorting individual cells into wells for downstream sequencing does not provide adequate throughput needed for meaningful analysis of the epigenetic states of the cells. To address this challenge, this research team developed a new methodology to analyze properties of single cells by labeling cell nuclei with DNA "barcodes" and distributing them using the SH800 sorter from Sony Biotechnology.


  • Pandemic Prevention: The Sprint Toward Protective Antibody Treatments

    01 Jul 2019

    Can antibodies be used as potential complements to vaccines? This team scours the planet looking for human donors to isolate PBMCs from those exposed to Rift Valley Fever in Kenya, to Ebola survivors. Supporting this important work, the Sony SH800 cell sorter has become an essential tool to isolate the right cells for a pipeline to generate antibody sequences that will ultimately build effective medical countermeasures.