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- Sony Biotechnology
- Sony Biotechnology
CD129 is the ligand binding subunit of IL-9 receptor (IL-9R or IL-9Rα). It is a type I transmembrance glycoprotein belonging to the hematopoientin receptor superfamily. The signal transducing subunit is common gamma chain (γc, CD132), which is shared with receptors for IL-2, IL-4, IL-7, and IL-21. The mouse IL-9R has 468aa and is about 52.2 kD. Besides modulating immune response, signals through IL-9 and IL-9R are also invoved in allergy and inflammatory disorders.
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.