Description

Tubulin is the main component of microtubules. In adults, tubulin β 3 (TUBB3) is primarily expressed in neurons and is commonly used as a neuronal marker. It plays an important role in neuronal cell proliferation and differentiation. Mutations in this gene cause congenital fibrosis of the type 3 extraocular muscles. Tubulin β 3 (TUBB3) is also found in a wide range of tumors. Studies indicate that it is a predictive and prognostic marker in various tumors.

Formulation

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.0 microg per ml. For immunofluorescent staining, the suggested use of this reagent is 1 - 5 microg per ml. It is recommended that the reagent be titrated for optimal performance for each application.