FX500 Exchangeable Fluidics Cell Sorter

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Innovative Fluidics

The FX500 features a unique replaceable fluidics system which includes an E-beam irradiated sorting chip and PEEK sample line, as well as a gamma irradiated sheath line assembly.

These single use consumables can be easily exchanged between experimental runs to control the sample-to-sample carryover.

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E-beam irradiated sorting chip, PEEK sample line and gamma irradiated sheath line can be easily exchanged between experiments to control sample-to-sample carryover.


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E-beam irradiated PEEK sample line.

Sample Line

The PEEK sample line introduces the sample into the E-beam irradiated sorting chip. Exchanging these single-use consumables between experiments controls sample-to-sample carryover.


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Gamma irradiated sheath line assembly, Chip connector.

Sheath Line Assembly

The sheath line assembly is made of gamma irradiated sheath line that can be linked to multiple sheath bags and connected to the chip using the chip connector.

The absence of fluidics pumps and inline valves in this design allows for an easy replacement of the sheath line as needed.


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Stainless sheath tank with removable rack for sheath bags.

Sheath Tank

A unique pressurized stainless sheath tank encloses a removable rack where sheath bags can be mounted. The sheath fluid from all the bags is channeled from a single sheath line to the chip.


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Three sizes of sorting chips are available including 70-μm and 100-μm sizes.

Microfluidics Sorting Chip

The E-beam irradiated sorting chip acts as an integrated flow cell/nozzle and can be easily installed and removed.

The sample and sheath fluid are injected into the chip's micro-fluidic channels from inlet ports. Excitation lasers interrogate the sample within the chip, and then the sample it passes through, and is sorted as droplets. The chip is directly connected to the waste line and can be declogged using software commands.

Unlike traditional systems that require nozzles to be removed for manual cleaning, the FX500 system uses an automated purge and prime cycle triggered by the software to clear the chip. A chip can be used continuously without removing it. The chip is available in 70-μm and 100-μm allowing researchers to easily adapt the system to various cell sizes.