Unleashing the Potential of Multiparameter Selection Using the CGX10 System to Drive Next-Generation Cell Therapies
For large-scale enrichment and isolation of immune cells or stem cells for cell therapy applications, common cell purification platforms separate cells based on a single surface antigen. Enrichment based on multiple cell surface markers or differing expression levels of these markers often requires a traditional cell sorter. In this webinar, we describe the CGX10 Cell Isolation System from Sony Biotechnology, a fully closed system suitable for GMP-compliant cell sorting. The CGX10 Cell Isolation System utilizes a novel microfluidics technology to achieve high purity cell isolation within a closed, sterile microfluidics chip.
The webinar also provides examples of how the CGX10 Cell Isolation System is used in protocols for driving next-generation cell therapies by employing multiparameter selection. We show how the system can be integrated into various cell and gene therapy manufacturing pipelines such as T-cell, regulatory T-cell (Treg), stem cell, and NK cell based cell therapies.
Key Learning Objectives:
- Explore the benefits, features, and usage of the CGX10 Cell Isolation System.
- Discover how the CGX10 can sort naïve T-cell subsets at high purity and viability for CAR-T platforms.
- Review application data for sorting of ultra-rare, naive Tregs directly from a leukopak for Treg therapy platforms.
- Learn how the CGX10 is used in iPSC derived cell therapy product pipelines for purifying differentiated cell types prior to formulation.
Who should attend
This webinar will benefit cell therapy specialists, scientists, and engineers working in the fields of cell and gene therapy manufacturing at the research, process development, or manufacturing stage. The session will be relevant for diverse applications such as CAR-Treg or Treg therapy, CAR-T therapy, TIL based therapy, CAR-NK therapy, immune cell therapy, and stem cell therapy.
Speaker
Brian Gelfand, PhD
Field Applications Scientist
Sony Biotechnology
Brian Gelfand earned his PhD at The Waksman Institute of Microbiology at Rutgers University, where he studied non-coding RNA function and transcriptomics. After graduation, he conducted genomic research in several species. He then gained experience in flow cytometry and cell sorting combined with genomic applications at start-up companies. At Sony Biotechnology since 2020, Brian has had specialized roles as Product Lead and Technical Sales Specialist for the CGX10 system.