Multiplexed Phenotyping and High-Resolution Cell Sorting for the Identification, Isolation, and Expansion of Novel Natural Killer Cell Subsets with Optimized Functionality
Presented by Select Science
The field of cancer immunotherapy has expanded significantly over the past decade, with huge improvements seen in patient outcomes for certain indications. However, there are major issues with the use of cell therapies for solid tumors. These include the immunosuppressive tumor microenvironment, poor trafficking of cells to tumors, and lack of targetable antigens at sufficient density to differentiate from healthy tissue. The use of natural killer cells for solid tumor therapy represents a novel and exciting approach that could address many of these limitations.
Join this free educational webinar to learn about the approaches used to accelerate the development of natural killer cell therapies by identifying unique NK cells isolated by sorting subsets with varied behaviors from peripheral blood.
Learning objectives:
- Learn about the development and behavior of NK cells in the context of cancer
- Understand how 3D tumoroids can be leveraged to explore the complexity of antitumor response mediated by NK cells
- Understand the multiplexed strategies used in this project that include sorting unique subsets of NK cells from peripheral blood to accelerate the development of anticancer therapies
Who should attend
This webinar will provide insights to researchers who want to develop cell therapies against solid tumors and want to learn how NK cells can be used for novel antitumor therapies. The presenter will discuss multiplexed approaches in which NK cells sorted from healthy human donors are rigorously characterized and studied for their antitumor immune responses.
Speaker
Nina Horowitz
Doctoral Candidate
Department of Bioengineering
Stanford University
Nina Horowitz is a doctoral candidate in the Bioengineering Department at Stanford University. She is currently carrying out research in the laboratory of Dr. John Sunwoo, an otolaryngology surgeon. Her interests lie at the intersection of synthetic biology, bioengineering, oncology, and immunology. Her current research focuses on the development of a new generation of highly effective and affordable cancer immunotherapies for patients with solid tumors. She holds an MS in Bioengineering from Stanford University and has previously researched at Williams College and Boston University.